
More people are starting to ask questions about what their clothes are actually made of…and for good reason. As more of us become aware of the chemicals used throughout the fashion industry, non-toxic clothing is becoming more appealing.
Many conventional garments are made with synthetic fibers, chemical dyes, wrinkle-resistant finishes, stain treatments, and other processing methods that aren’t always disclosed to consumers. While it’s nearly impossible to find clothing completely free from every chemical, some brands are taking meaningful steps toward using safer materials and more responsible manufacturing practices.
At Sustainably Chic, we typically look for brands that prioritize natural fibers, avoid unnecessary chemical treatments, and use certifications like OEKO-TEXยฎ and GOTS to help verify safer production standards.
If you’re looking to build a lower-tox wardrobe, these are some of our favorite non-toxic clothing brands for women.
What Is Non-Toxic Clothing?
Non-toxic clothing refers to garments made with a focus on minimizing potentially harmful chemicals throughout the production process.
This often includes avoiding or reducing exposure to:
- PFAS (forever chemicals)
- Formaldehyde
- Heavy metals
- Phthalates
- Certain azo dyes
- Chemical finishing treatments
Because regulations vary widely across the fashion industry, certifications can help consumers identify products that have been tested for specific substances.
What We Look for in Non-Toxic Clothing Brands
No brand is perfect, but we generally prioritize companies that focus on:
1. Natural Fibers
Our favorite materials include:
Natural fibers don’t shed plastic microfibers the way synthetic fabrics do and often require fewer chemical treatments.
2. Third-Party Certifications
Some certifications we look for include:
- GOTS (Global Organic Textile Standard)
- OEKO-TEXยฎ Standard 100
- MADE SAFEยฎ
- Fair Trade Certifiedโข
3. Transparency
We appreciate brands that openly discuss:
- Materials
- Manufacturing
- Dyeing processes
- Supply chains
Transparency doesn’t automatically make a brand sustainable, but it’s an important step.
Our Top Picks for Non-Toxic Clothing Brands for Women

1. Pact
Best For: Everyday basics
Pact is one of our favorite affordable brands for building a lower-tox wardrobe. The company uses GOTS-certified organic cotton throughout much of its collection, which helps reduce exposure to many of the pesticides and chemicals commonly associated with conventional cotton farming. Pact also manufactures many of its products in Fair Trade Certified factories and prioritizes simple, everyday basics that can be worn for years. While no clothing can be considered completely chemical-free, Pact’s focus on organic fibers and third-party certifications makes it a great option for those looking to reduce their reliance on synthetic fabrics and build a wardrobe centered around natural materials.

2. MATE the Label
Best For: Lounge and basics
When people ask us about non-toxic clothing brands, MATE the Label is often one of the first names that comes to mind. The brand has built its entire identity around creating clothing with organic and natural materials. MATE primarily uses GOTS-certified organic cotton, linen, and natural dyes throughout its collections. The company is also highly transparent about its manufacturing processes and frequently educates consumers about textiles, chemicals, and lower-tox living. For anyone looking to build a minimalist wardrobe focused on natural fibers, MATE remains one of the best options available.

3. Kent
Best for: Plastic-free underwear
Kent is best known for creating organic cotton underwear (completely plastic-free) and everyday essentials with simplicity and transparency at the forefront. The brand focuses on GOTS-certified organic cotton and avoids many of the synthetic materials commonly found in intimate apparel. Since underwear sits directly against the skin for long periods of time, many consumers prefer natural fibers over synthetic fabrics whenever possible. Kent’s minimalist approach to design and material selection makes it an excellent choice for those looking to reduce unnecessary chemical exposure while prioritizing comfort.

4. Harvest & Mill
Best For: American-made basics
Harvest & Mill takes a unique approach to non-toxic clothing by focusing on American-grown organic cotton and local manufacturing. The brand’s collections are made with natural fibers and often feature undyed options, which can help reduce exposure to additional dyes and textile treatments. Their commitment to keeping production close to home also creates greater transparency throughout the supply chain. If you’re looking for basics made with fewer inputs and a strong emphasis on natural materials, Harvest & Mill is worth exploring.

5. Fair Indigo
Best For: Organic cotton wardrobe staples
Fair Indigo combines Fair Trade principles with organic cotton fabrics to create timeless wardrobe staples. Much of the brand’s collection is made with GOTS-certified organic cotton, helping to reduce the use of many agricultural chemicals associated with conventional cotton production. Fair Indigo also places a strong emphasis on ethical manufacturing and long-lasting quality. Their pieces aren’t designed around fast-moving trends but instead focus on classic silhouettes that can remain in your wardrobe for years.

6. LA Relaxed
Best For: USA-made linen & cotton essentials
LA Relaxed has become one of our favorite brands for elevated basics made from natural fibers. The company manufactures locally in Los Angeles and frequently uses linen, organic cotton, and TENCELโข throughout its collections. Linen, in particular, is one of our favorite fabrics for a lower-tox wardrobe because it is naturally breathable and requires fewer chemical inputs than many synthetic alternatives. LA Relaxed focuses on timeless silhouettes rather than trend-driven fashion, making their clothing easy to wear season after season.

7. Eileen Fisher
Best For: Elevated wardrobe staples
Eileen Fisher has spent decades helping shape the sustainable fashion movement. While the brand offers a variety of materials, it has consistently increased its use of organic fibers, responsible wool, and lower-impact fabrics over the years. Eileen Fisher also provides substantial transparency regarding its supply chain and environmental initiatives. Many of the brand’s garments are OEKO-TEX certified or made with organic materials, helping us identify products produced with stricter standards. For shoppers seeking timeless investment pieces made from natural fibers and supported by one of the industry’s most established sustainability programs, Eileen Fisher remains a wonderful option.

8. Known Supply
Best For: Ethical basics
Known Supply takes a refreshingly human approach to fashion. Every garment is signed by the person who made it, helping connect us directly with the makers behind their clothing. The brand uses organic cotton throughout much of its collection and prioritizes ethical manufacturing. From a non-toxic perspective, we love Known Supply’s focus on natural fibers and transparency. Their basics are designed to be comfortable, versatile, and long-lasting. Rather than encouraging overconsumption, Known Supply focuses on creating everyday essentials that you’ll actually want to wear for years.

9. Outerknown
Best For: Casual everyday wear
Founded by professional surfer Kelly Slater, Outerknown has become one of the most recognizable names in sustainable fashion. The brand uses a variety of eco-friendly materials throughout its collections, including organic cotton, regenerative cotton and hemp. We appreciate the company’s commitment to transparency and responsible sourcing, as well as its focus on creating durable clothing designed to be worn for years. For those looking to build a lower-tox wardrobe, Outerknown offers a strong selection of comfortable, everyday staples made with thoughtfully sourced materials.

10. Christy Dawn
Best For: Dresses
Christy Dawn has become a favorite among sustainable fashion lovers thanks to its beautiful dresses and commitment to more responsible materials. The brand is particularly known for using regenerative cotton and deadstock fabrics in many of its collections. Regenerative cotton farming focuses on improving soil health while reducing the need for many conventional agricultural inputs. Christy Dawn’s pieces are designed with longevity in mind, featuring timeless silhouettes that can be worn season after season. Their collections prove that lower-tox fashion can still feel romantic, feminine, and special.

11. Passion Lilie
Best For: Fair Trade dresses
Passion Lilie combines Fair Trade production with natural materials to create colorful clothing that feels both fun and feminine. The brand works directly with artisan partners and places a strong emphasis on ethical manufacturing practices. Many of its garments are made from organic cotton, helping reduce exposure to some of the pesticides commonly used in conventional cotton farming. For shoppers seeking non-toxic clothing that balances comfort, color, and conscious production, Passion Lilie is a wonderful brand to explore.

12. Kotn
Best For: Cotton basics
Kotn has built its reputation around high-quality cotton basics and transparent supply chains. The brand works directly with cotton farming communities in Egypt and prioritizes natural fibers throughout their collections. Cotton remains one of the most popular fabrics for those seeking lower-tox clothing because of its breathability and comfort, especially when responsibly sourced. Kotn’s timeless essentials are designed to become everyday staples rather than disposable fashion purchases. We appreciate the brand’s focus on quality over quantity and its ongoing commitment to improving social and environmental impact. Their simple, elevated basics make it easy to build a wardrobe centered around natural materials.

13. Jungmaven
Best For: Hemp clothing
Jungmaven has been championing hemp clothing long before it became trendy. Hemp is one of our favorite natural fibers because it requires relatively few inputs, is incredibly durable, and becomes softer with wear. The brand combines hemp with other natural fibers to create comfortable basics designed for everyday life. From a non-toxic perspective, hemp offers an awesome alternative to synthetic materials while providing great breathability. Jungmaven’s pieces are simple, versatile, and built to last.

14. Colorful Standard
Best For: Organic essentials
Colorful Standard is known for its vibrant basics and commitment to responsible production. We always say this brand is the more ethical & sustainable version of American Apparel. They use organic cotton and OEKO-TEX-certified dyes throughout their collection, and focus on wardrobe essentials rather than fast-moving trends. Their extensive color range proves that lower-tox clothing doesn’t have to be limited to neutrals. For shoppers who want comfortable basics in an array of colors, this brand offers plenty of options.

15. Toad&Co
Best For: Casual comfort
Toad&Co creates casual clothing designed for everyday adventures while incorporating more responsible materials throughout its collections. The brand frequently uses organic cotton, hemp, and other lower-impact fibers, and they focus on comfort, versatility, and durability, all of which encourage clothing to stay in circulation longer. While Toad&Co isn’t marketed exclusively as a non-toxic clothing brand, its commitment to natural materials and responsible sourcing makes it a great option for consumers looking to reduce synthetic fabrics in their closets. Their easy-to-wear pieces are particularly well suited for travel, outdoor activities, and everyday life.

16. Happy Earth
Best For: Affordable sustainable clothing
Happy Earth focuses on creating accessible sustainable clothing while supporting environmental initiatives. The brand uses organic cotton and other eco-friendly materials in all of their designs. For those interested in non-toxic fashion, the brand’s emphasis on organic materials and cute prints is very appealing. Happy Earth shows that building a lower-tox wardrobe doesn’t have to be complicated or expensive.

17. Son de Flor
Son de Flor has built a loyal following around its timeless linen clothing inspired by classic European design. The brand’s collections are made primarily from linen, one of our favorite natural fibers for a lower-tox wardrobe. Linen is breathable, durable, and requires fewer resources than many conventional fabrics. Son de Flor’s dresses, skirts, and tops are designed to transcend trends and remain wearable for years. We also love that many of the brand’s fabrics are OEKO-TEX certified, helping provide additional reassurance for those looking to reduce exposure to potentially harmful substances in clothing.

18. People of Leisure
Best For: Graphic tees and vintage-inspired basics
People of Leisure creates laid-back clothing inspired by vintage style while incorporating more responsible materials and manufacturing practices. The brand uses organic cotton in many of its pieces, which is a rare find in the graphic tee world. Their graphic tees, sweatshirts, and everyday basics offer a more conscious alternative to conventional apparel.

19. Coyuchi
Best For: Organic home and loungewear
While Coyuchi is best known for its organic bedding and home textiles, the brand also offers a growing collection of apparel and loungewear made with GOTS-certified organic cotton. Coyuchi has long been a leader in the organic textile space and maintains exceptionally high standards when it comes to material sourcing and production. For consumers concerned about chemical exposure, the brand’s commitment to organic fibers and rigorous certifications makes it particularly appealing. Their clothing is ideal for those seeking soft, natural fabrics that feel good against the skin and support a lower-tox lifestyle.

20. Organsk
Best for: Clean, sustainable denim
Organsk is one of the few denim brands specifically focused on creating jeans with both sustainability and lower-tox materials in mind. The brand uses GOTS-certified organic cotton and prioritizes fabrics that have been tested to OEKO-TEXยฎ standards, helping reduce exposure to many of the chemicals commonly associated with conventional denim production. This is particularly important because traditional denim manufacturing can involve significant amounts of pesticides, synthetic dyes, and finishing treatments. We love that Organsk focuses on transparency and keeps its collections intentionally small rather than chasing constant trends. If you’re trying to build a lower-tox wardrobe without giving up your favorite pair of jeans, this brand is definitely worth exploring.

21. Organic Basics
Best for: Eco-friendly basics
Organic Basics has become one of the most recognized brands in the sustainable basics category. The company uses a combination of organic cotton, TENCELโข, and other eco-friendly materials. For those building a non-toxic wardrobe, Organic Basics offers a great selection of underwear, loungewear, activewear, and everyday essentials made with more thoughtfully sourced fabrics. Rather than chasing trends, Organic Basics focuses on creating practical pieces that can become the foundation of a long-lasting wardrobe.

22. Q for Quinn
Best for: Organic cotton socks & underwear
Q for Quinn specializes in organic cotton socks, underwear, and everyday essentials for both children and adults. The brand has become particularly popular among families looking to reduce exposure to unnecessary chemicals in products worn close to the skin. Many of its products are made with GOTS-certified organic cotton and OEKO-TEX-certified materials. We love the brand’s commitment to transparency and its focus on practical basics that are comfortable enough for everyday wear. Q for Quinn is an excellent option for anyone wanting to start their non-toxic clothing journey with foundational wardrobe pieces.

23. Conscious Step
Best for: Organic cotton socks that give back
Conscious Step may be best known for its colorful socks, but the brand’s commitment to organic cotton, ethical production and giving back makes it a great addition to this list. Their products are made with GOTS-certified organic cotton and produced in Fair Trade Certified facilities. While socks may seem like a small part of a wardrobe, they’re often one of the most frequently worn items we own. We also love the brand’s social impact initiatives, which support a variety of nonprofit organizations through product purchases.

24. Subset
Best for: Organic cotton underwear & bras
Formerly known as Knickey, Subset focuses on creating lower-tox underwear and basics using GOTS-certified organic cotton. Since underwear is worn directly against the skin for extended periods of time, many of us prioritize natural fibers when shopping in this category. Subset combines organic materials with transparent manufacturing practices and even offers a recycling program for worn-out underwear. We love the brand’s straightforward approach and commitment to helping consumers build healthier wardrobes from the inside out. Their comfortable essentials are a great option for anyone looking to replace synthetic undergarments with more natural alternatives.

25. Katruss
Best For: Luxury clothing made from innovative plant-based fabrics
Katruss takes a unique approach to non-toxic fashion by focusing on plant-based textiles rather than conventional synthetic materials. The brand works with innovative natural fibers derived from sources like rose, banana, aloe, and other plants, creating fabrics that are breathable, biodegradable, and designed for comfort. Katruss offers a refreshing perspective on what modern non-toxic clothing can look like. While no clothing is completely free from every chemical input, the brand’s focus on biodegradable, plant-derived materials makes it a wonderful option for those building a wardrobe centered around natural fibers.
How to Build a Lower-Tox Wardrobe
You don’t need to replace everything overnight.
A more practical approach is to prioritize:
- Natural fibers when possible
- Organic cotton basics
- Fewer synthetic fabrics
- Higher-quality pieces
- Brands with strong transparency
Progress matters more than perfection.
Frequently Asked Questions
What is the safest fabric to wear?
Organic cotton is often considered one of the safest and most accessible clothing materials because it avoids many pesticides used in conventional cotton production.
Is OEKO-TEX clothing non-toxic?
OEKO-TEX Standard 100 tests finished products for a wide range of potentially harmful substances, making it one of the most helpful certifications for consumers seeking lower-tox clothing.
Is polyester toxic?
Polyester itself is widely used in clothing, but many consumers choose to limit synthetic fibers because they are petroleum-based and can shed microplastics during washing.
What certifications should I look for?
We typically recommend looking for:
- GOTS
- OEKO-TEX Standard 100
- MADE SAFE
- Fair Trade Certified
Final Thoughts
Building a lower-tox wardrobe doesn’t have to happen overnight. Choosing natural fibers, supporting transparent brands, and prioritizing quality over quantity can go a long way toward reducing exposure to unnecessary chemicals while creating a wardrobe you’ll love for years to come.
As always, we believe the most sustainable piece of clothing is the one you’ll actually wear.
About the Author
Natalie Kay Costello is the founder of Sustainably Chic and has been writing about sustainable fashion for over a decade. Her work focuses on ethical brands, natural fabrics, and helping consumers navigate greenwashing in the fashion industry.


















































